I was a fast-food worker. Let me tell you about burnout. - Emily Guendelsberger
If you had to make a rat depressed, how do you think you'd go about it? To test your new antidepressant, you need an efficient method of making a lot of rats exhibit anhedonia - that is, making them lose interest in things they used to enjoy, like sugar. It turns out you don't need to traumatize them. The most reliable protocol is "chronic mild stress." ... remove all predictability and control from the animal's life. Then take notes as they gradually lose interest in being alive.
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